Mukinbudin is a town located in the North Eastern Wheatbelt region of Western Australia, approximately 293 kilometres (182 mi) east of Perth and 80 kilometres (50 mi) north of Merredin near Lake Campion. It is the main town in the Shire of Mukinbudin.
The present Shire of Mukinbudin was settled by pastoralists who in the 1870s took up large leases in excess of 20,000 acres (81 km²) to run sheep and by sandalwood cutters and miners en route to the goldfields. In 1910 the first of the farmers arrived to commence wheat growing on their 1,000 acres (4 km²) block and it was some time before they added stock to what had been entirely a wheat growing enterprise. An extension of the Mt Marshall railway line to Mukinbudin and Lake Brown was approved in 1922 and opened in October 1923. The townsite was gazetted in 1922.